{"id":6651,"date":"2024-11-15T12:56:19","date_gmt":"2024-11-15T12:56:19","guid":{"rendered":"https:\/\/staging.prodottigianni.com\/3d-genomics\/"},"modified":"2025-10-02T11:26:33","modified_gmt":"2025-10-02T11:26:33","slug":"3d-genomics","status":"publish","type":"page","link":"https:\/\/www.prodottigianni.com\/en\/life-science-services\/3d-genomics\/","title":{"rendered":"3d Genomics"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"6651\" class=\"elementor elementor-6651 elementor-936\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-895b927 e-con-full e-flex e-con e-parent\" data-id=\"895b927\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-13757ee e-con-full e-flex e-con e-child\" data-id=\"13757ee\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-743cc3d elementor-widget elementor-widget-heading\" data-id=\"743cc3d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">3D Genomics<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e14db50 elementor-widget elementor-widget-heading\" data-id=\"e14db50\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Prodotti Gianni provides the \u201cextensive experience of its partners for the\u201d reliable execution of service experiments and custom production requests.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c18fe7b e-flex e-con-boxed e-con e-parent\" data-id=\"c18fe7b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-071b8fc e-con-full e-flex e-con e-child\" data-id=\"071b8fc\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-43f9010 elementor-widget elementor-widget-heading\" data-id=\"43f9010\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">3D Genomics<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-00e80df elementor-widget elementor-widget-text-editor\" data-id=\"00e80df\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">3D genomics provides unprecedented access to the sequence, structure, and regulatory landscape of any genome. The Hi-C (High Throughput Chromatin Conformation Capture) technique that  <\/span><span style=\"font-weight: 400;\">allows visualization of how temporal and spatial changes in chromatin alter gene regulation and cellular functions, <\/span><span style=\"font-weight: 400;\">combines the Proximity Ligation assay with the NGS approach.<\/span><\/p><p><span style=\"font-weight: 400;\">This technique has been optimized in Arima Hi-C kits to achieve a more flexible, robust, and faster protocol that can be done in a single tube using 2 or 4 patented restriction enzymes and producing a much higher percentage of <\/span><i><span style=\"font-weight: 400;\">long-range cis interactions<\/span><\/i><span style=\"font-weight: 400;\"> compared to the classic approach at a lower cost.<\/span> <span style=\"font-weight: 400;\">There are multiple applications for 3D genomics. In cancer research,  <\/span><i><span style=\"font-weight: 400;\">it enables the discovery <\/span><\/i><span style=\"font-weight: 400;\">of structural variants for a complete understanding of disease mechanisms, <\/span><i><span style=\"font-weight: 400;\">biomarker discovery, and new therapeutic approaches thanks to insights into the sequence, structure, and regulatory landscape of cancer genomes.<\/span><\/i><span style=\"font-weight: 400;\"> <\/span><\/p><p><span style=\"font-weight: 400;\">  Understanding how spatial relationships in genome structure influence gene regulation, cell development, and pathological processes supports epigenetic studies, while the \u201cassembly of chromosome-scale genomes helps explore the\u201d evolution of species.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>3D Genomics Prodotti Gianni provides the \u201cextensive experience of its partners for the\u201d reliable execution of service experiments and custom production requests. 3D Genomics 3D genomics provides unprecedented access to the sequence, structure, and regulatory landscape of any genome. The Hi-C (High Throughput Chromatin Conformation Capture) technique that allows visualization of how temporal and spatial [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_mc_calendar":[],"footnotes":""},"class_list":["post-6651","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\r\n<title>3d Genomics - Prodotti Gianni<\/title>\r\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\r\n<link rel=\"canonical\" href=\"https:\/\/www.prodottigianni.com\/en\/life-science-services\/3d-genomics\/\" \/>\r\n<meta property=\"og:locale\" content=\"en_US\" \/>\r\n<meta property=\"og:type\" content=\"article\" \/>\r\n<meta property=\"og:title\" content=\"3d Genomics - Prodotti Gianni\" \/>\r\n<meta property=\"og:description\" content=\"3D Genomics Prodotti Gianni provides the \u201cextensive experience of its partners for the\u201d reliable execution of service experiments and custom production requests. 3D Genomics 3D genomics provides unprecedented access to the sequence, structure, and regulatory landscape of any genome. 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