What is PDRN
PDRN (INCI: Sodium DNA) is a naturally derived bioactive ingredient composed of purified DNA fragments that can physiologically stimulate tissue regeneration, improve skin quality, and promote wound healing. It is generally extracted from salmon or trout gonads, highly purified for medical and cosmetic use
In the past 18-24 months, PDRN has gone from an ingredient used almost exclusively in clinical treatments to a key active in home-use cosmetics, with strong traction in Asian and K-Beauty markets.
Trend analysis data indicate:
– Trend Score 9.9, a sign of accelerated and not yet mature growth
– Rapid shift toward serums, skin boosters, and leave-on products inspired by cosmetic dermatology
In parallel, the market is evolving toward vegan alternatives:
– Several international brands and K-Beauty have already introduced PDRNs of plant or microbial origin
– The goal is to maintain claims of regeneration and efficacy while reducing the limitations associated with animal origin
Vegan PDRN: from market trend to formulation solution
In this context, the Vegan PDRN represents the most consistent evolution of the trend, especially for:
– high-performance anti-aging
– clinically inspired skin booster
– Formulas geared toward elasticity, pores and skin barrier
Presperse (BioGenics) has developed a range of plant-derived, probiotic Vegan PDRNs designed to offer the same regenerative function to traditional PDRN derived from salmon DNA while overcoming the limitations associated with animal origin.
The range includes three variants:
– Lacto-PDRN – from Ginseng via Lactobacillus plantarum
– Cica-PDRN – from Centella Asiatica
– Bakuchiol-PDRN – from Psoralea Corylifolia
Clinical Evidence: Cica-PDRN 1% (4 weeks)
In clinical trials conducted on formulations containing Cica-PDRN 1%, significant improvements were observed as early as 4 weeks:
– +38.8% face lift
– +23.3% skin elasticity
-57% pore number and -31% pore depth
– +81.6% recovery of skin barrier after chemical stress (SLS)
Results confirm the regenerative efficacy of Vegan PDRN on key parameters for anti-aging, skin booster and barrier-care formulations.
